CaMKK2-IN-1
CaMKK2-IN-1 is a selective, ligand-efficient inhibitor of CaMKK2, with IC50 of 7 nM[1].
Product Specifications
CAS Number
[3032691-65-6]
UNSPSC
12352005
Target
Calmodulin
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/camkk2-in-1.html
Concentration
10mM
Purity
98.77
Solubility
DMSO : 40 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CCOC1=CC=C(C(C2=CC(C3CCCC3)=C(C(O)=O)C=C2)=NC=N4)C4=C1
Molecular Formula
C22H22N2O3
Molecular Weight
362.42
References & Citations
[1]Young Chen, et al. Identification of Small Molecule Inhibitors and Ligand Directed Degraders of Calcium/Calmodulin Dependent Protein Kinase Kinase 1 and 2 (CaMKK1/2) . J Med Chem. 2023 Dec 14;66 (23) :15750-15760.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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