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Deruxtecan-d4-1

Deruxtecan-d4-1 is the deuterium labeled Adenosine Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

Product Specifications

CAS Number

2760715-88-4

Product Name Alternative

MC-GGFG-DXD-d4-1

UNSPSC

12352005

Target

Drug-Linker Conjugates for ADC; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Antibody-drug Conjugate/ADC Related; Others

Field of Research

Others

Solubility

10 mM in DMSO

Smiles

O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NC([2H])([2H])OC([2H])([2H])C(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O

Molecular Formula

C52H52D4FN9O13

Molecular Weight

1038.08

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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