PROTAC PRMT3 degrader 1
Product Specifications
UNSPSC Description
PROTAC PRMT3 degrader 1 (compound 11) is a PROTAC degrader targeting PRMT3. PROTAC PRMT3 degrader 1 can inhibit the growth of acute leukemia cells[1].
Target Antigen
Histone Methyltransferase; PROTACs
Type
Reference compound
Related Pathways
Epigenetics;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-prmt3-degrader-1.html
Smiles
O=C([C@@H]1NC2([C@]3([C@H]1C4=CC=CC(Cl)=C4F)C(NC5=C3C=CC(Cl)=C5)=O)CCCCC2)NCCCCCCCCNC(C6CN(C(CNC(NC7=CC8=C(C=NC=C8)C=C7)=O)=O)C6)=O
Molecular Weight
899.88
References & Citations
[1]Zou W, et al. Discovery of PRMT3 Degrader for the Treatment of Acute Leukemia. Adv Sci (Weinh). 2024 Aug 9:e2405963.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159728/PROTAC-PRMT3-degrader-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159728/
Clinical Information
No Development Reported
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