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DDIT3 Recombinant Rabbit Monoclonal Antibody [PSH07-65]

DNA damage-inducible transcript 3, also known as C/EBP homologous protein (CHOP), is a pro-apoptotic transcription factor that is encoded by the DDIT3 gene. It is a member of the CCAAT/enhancer-binding protein (C/EBP) family of DNA-binding transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis and has an important role in the cell's stress response.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

C/EBP homologous protein antibody C/EBP Homology Protein antibody C/EBP zeta antibody C/EBP-homologous protein 10 antibody C/EBP-homologous protein antibody CCAAT/enhancer binding protein homologous protein antibody CEBPZ antibody CHOP 10 antibody CHOP antibody CHOP-10 antibody CHOP10 antibody DDIT 3 antibody DDIT-3 antibody Ddit3 antibody DDIT3_HUMAN antibody DNA Damage Inducible Transcript 3 antibody DNA damage-inducible transcript 3 protein antibody GADD 153 antibody GADD153 antibody Growth Arrest and DNA Damage Inducible Protein 153 antibody Growth arrest and DNA damage inducible protein GADD153 antibody Growth arrest and DNA damage-inducible protein GADD153 antibody MGC4154 antibody

Abbreviation

DDIT3, CHOP, CHOP10, GADD153

Swiss Prot

P35638 Human, P35639 Mouse, Q62857 Rat

Cellular Locus

Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human DDIT3 aa 1-169.

Isotype

IgG

Clone

PSH07-65

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, FC

Positive Control

HeLa treated with 2μg/mL tunicamycin for 8 hours cell lysate, C2C12 treated with 2μg/mL thapsigargin for 8 hours cell lysate, C6 cell lysate, C6 treated with 2μg/mL tunicamycin for 8 hours cell lysate, HeLa cells treated with 2μg/mL tunicamycin for 8 hours, C2C12 cells treated with 2μg/mL thapsigargin for 8 hours, C6 cells treated with 2μg/mL tunicamycin for 8 hours.

Concentration

1 mg/mL

Dilution

WB: 1:5,000 ;IF-Cell: 1:100 ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 19 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

Frequently Asked Questions

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