JAMM protein inhibitor 2
JAMM protein inhibitor 2 (compound 180) is a potent JAMM protease inhibitor with IC50s of 10 μM, 46 μM and 89 μM for thrombin, Rpn11 and MMP2, respectively. JAMM protein inhibitor 2 can be used for researching anticancer[1]
Product Specifications
CAS Number
[848249-35-4]
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jamm-protein-inhibitor-2.html
Purity
98.20
Solubility
DMSO : 14.71 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=CC=C(N2CCCC2)C=C1C)COC3=CC=CC=C3CC
Molecular Formula
C21H26N2O2
Molecular Weight
338.44
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Han-Jie Zhou, et al. Methods and compositions for jamm protease inhibition. WO2013123071A1 (compound 180)
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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