Pyridoxal isonicotinoyl hydrazone
Product Specifications
UNSPSC Description
Pyridoxal isonicotinoyl hydrazone (PIH) is a lipophilic, tridentate Fe-chelating agent that shows high Fe chelation efficacy[1].
Target Antigen
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pyridoxal-isonicotinoyl-hydrazone.html
Purity
99.96
Solubility
DMSO : 7 mg/mL (ultrasonic;heat to 60°C)
Smiles
CC1=NC=C(C(/C=N/NC(C2=CC=NC=C2)=O)=C1O)CO
Molecular Weight
286.29
References & Citations
[1]Hermes-Lima M, et al. The iron chelator pyridoxal isonicotinoyl hydrazone (PIH) and its analogues prevent damage to 2-deoxyribose mediated by ferric iron plus ascorbate. Biochim Biophys Acta. 2000 Oct 18;1523(2-3):154-60.|[2]Landschulz W, et al. A lipophilic iron chelator can replace transferrin as a stimulator of cell proliferation and differentiation. J Cell Biol. 1984 Feb;98(2):596-601.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114758/Pyridoxal-isonicotinoyl-hydrazone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114758/Pyridoxal-isonicotinoyl-hydrazone-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
737-86-0
Available Sizes
Curated Selection
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