BN-82685
BN-82685 is a a quinone-based CDC25 inhibitor with IC50 of 201 nM, 117 nM, 109 nM, 160 nM, 249 nM, for CDC25C, CDC25C-cat, CDC25A, CDC25B2, CDC25B3, respectively. BN-82685 plays an important role in cancer research[1].
Product Specifications
CAS Number
[477603-18-2]
Product Name Alternative
IRC-083065
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bn-82685.html
Purity
99.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(NCCN(C)C)=CC1=O)C2=C1SC(C)=N2
Molecular Formula
C12H15N3O2S
Molecular Weight
265.33
Precautions
H302, H315, H319, H335
References & Citations
[1]Marie-Christine Brezak, et al. IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells. Int J Cancer. 2009 Mar 15;124 (6) :1449-56.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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