L-Leu-AMC (Highly Pure)

<strong>L-Leu-AMC (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2017490_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 324.8_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Leu-MCA, L-Leucine-7-amido-4-methylcoumarin, 7-L-Leucyl-4-methylcoumarinylamide_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Cheng T, Chepkirui C, Decock C, Matasyoh JC, Stadler M. Skeletocutins M-Q: biologically active compounds from the fruiting bodies of the basidiomycete Skeletocutis sp. collected in Africa Beilstein J Org Chem. 2019 Nov 19;15:2782-2789._x000D_ 2: Lecaille F, Naudin C, Sage J, Joulin-Giet A, Courty A, Andrault PM, Veldhuizen RA, Possmayer F, Lalmanach G. Specific cleavage of the lung surfactant protein A by human cathepsin S may impair its antibacterial properties Int J Biochem Cell Biol. 2013 Aug;45(8):1701-9._x000D_ 3: Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Autophagy. 2016;12(1):1-222._x000D_ 4: Zhang X, Luo K, Wang G, Nie Y, He B, Wu Y, Gu Z. Synthesis and inhibition study on tripeptide inhibitor modified poly(L-lysine) dendrimers J Biomater Appl. 2012 Jul;27(1):17-26._x000D_ 5: Beighton D, Radford JR, Naylor MN. Protease activity in gingival crevicular fluid from discrete periodontal sites in humans with periodontitis or gingivitis Arch Oral Biol. 1990;35(5):329-35._x000D_ 6: Chauke E, Pelle R, Coetzer THT. A single exon-encoded Theileria parva strain Muguga cysteine protease (ThpCP): Molecular modelling and characterisation Biochimie. 2023 Mar;206:24-35._x000D_ 7: Chandu D, Kumar A, Nandi D. PepN, the major Suc-LLVY-AMC-hydrolyzing enzyme in Escherichia coli, displays functional similarity with downstream processing enzymes in Archaea and eukarya. Implications in cytosolic protein degradation J Biol Chem. 2003 Feb 21;278(8):5548-56._x000D_ 8: Yoon MC, Ames J, Mosier C, Jiang Z, Podvin S, O'Donoghue AJ, Hook V. Distinct Dibasic Cleavage Specificities of Neuropeptide-Producing Cathepsin L and Cathepsin V Cysteine Proteases Compared to PC1/3 and PC2 Serine Proteases ACS Chem Neurosci. 2022 Jan 19;13(2):245-256._x000D_ 9: Robertson JD, Datta K, Biswal SS, Kehrer JP. Heat-shock protein 70 antisense oligomers enhance proteasome inhibitor-induced apoptosis Biochem J. 1999 Dec 1;344 Pt 2(Pt 2):477-85._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32308346">10: Xie RJ, Hu XX, Zheng L, Cai S, Chen YS, Yang Y, Yang T, Han B, Yang Q. Calpain-2 activity promotes aberrant endoplasmic reticulum stress-related apoptosis in hepatocytes World J Gastroenterol. 2020 Apr 7;26(13):1450-1462. </a>_x000D_ _x000D_ <strong>Products Related to L-Leu-AMC (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>