Swertianine
Swertianine is a hydroxyexanthone that can be isolated from Swertia decussata. Swertianine has antioxidant activity by inhibiting lipid peroxidation, scavenging DPPH and superoxide free radicals. Swertianine also inhibits γ-ray induced DNA damage of pBR322 with protective effect[1].
Product Specifications
CAS Number
[20882-75-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/swertianine.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(OC3=C1C(O)=CC(OC)=C3)C=CC(O)=C2O
Molecular Formula
C14H10O6
Molecular Weight
274.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Patro BS, et al. Antioxidant activities of Swertia decussata xanthones. Nat Prod Res. 2005 Jun;19 (4) :347-54.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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