Velutin
Velutin is an aglycone extracted from Flammulina velutipes, with inhibitory activity against melanin biosynthesis. Velutin reduces osteoclast differentiation and down-regulates HIF-1α through the NF-κB pathway[1][2].
Product Specifications
CAS Number
25739-41-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HIF/HIF Prolyl-Hydroxylase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/velutin.html
Purity
98.60
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(O)C(OC)=C2)OC3=CC(OC)=CC(O)=C13
Molecular Formula
C17H14O6
Molecular Weight
314.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Jung SH, et al. Velutin, an Aglycone Extracted from Korean Mistletoe, with Improved Inhibitory Activity against Melanin Biosynthesis. Molecules. 2019 Jul 12;24 (14) .|[2]Brito C, et al. Cytotoxicity and potential anti-inflammatory activity of velutin on RAW 264.7 cell line differentiation: Implications in periodontal bone loss. Arch Oral Biol. 2017 Nov;83:348-356
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LY402242 100 µg
C12orf24 (FAM216A) (NM_013300) Human Over-expression Lysate
Sign In for Pricing
View Details 