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Syk-IN-1

Syk-IN-1 (compound 4) is a potent Syk inhibitor, with an IC50 of 35 nM[1].

Product Specifications

CAS Number

1491150-77-6

UNSPSC

12352005

Target

Syk

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/syk-in-1.html

Purity

99.18

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC(C1=NN=C(N[C@@H]2CCCC[C@@H]2N)N=C1NC3=CC=CC4=C3NC=C4)=O

Molecular Formula

C18H22N8O

Molecular Weight

366.42

References & Citations

[1]Thoma G, et al. Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorg Med Chem Lett. 2015;25 (20) :4642-4647.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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