Syk-IN-1
Syk-IN-1 (compound 4) is a potent Syk inhibitor, with an IC50 of 35 nM[1].
Product Specifications
CAS Number
1491150-77-6
UNSPSC
12352005
Target
Syk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/syk-in-1.html
Purity
99.18
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC(C1=NN=C(N[C@@H]2CCCC[C@@H]2N)N=C1NC3=CC=CC4=C3NC=C4)=O
Molecular Formula
C18H22N8O
Molecular Weight
366.42
References & Citations
[1]Thoma G, et al. Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorg Med Chem Lett. 2015;25 (20) :4642-4647.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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