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Recombinant PGP9.5 Antibody

This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1) . Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinsons disease.

Product Specifications

UniProt

P09936

Reactivity

Human

Immunogen

Recombinant full-length human protein was used as the immunogen for the recombinant PGP9.5 antibody.

Clonality

Recombinant

Clone

UCHL1/4556R

Conjugation

Unconjugated

Field of Research

Cell Biology

Purification

Protein A affinity chromatography

Dilution

Western blot: 2-4ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the recombinant PGP9.5 antibody should be determined by the researcher.

Tested Applications

IHC-P, WB

Host or Source

Rabbit

Preservative

0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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