IDX375
IDX375 is a novel non-nucleoside inhibitor with selective inhibitory activity against HCV NS5B. IDX375 has good selectivity for genotypes 1a and 1b. The structure and binding site of IDX375 were confirmed by X-ray cocrystal studies[1].
Product Specifications
CAS Number
[1162665-52-2]
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/idx375.html
Smiles
CS(=O)(NC1=CC=C(C2=C1)NC(C3=C(O)[C@H](C(C)(C)C)N(CCC(C)(C)C)C3=O)=N[P@]2(OCC)=O)=O
Molecular Formula
C24H37N4O6PS
Molecular Weight
540.61
References & Citations
[1]Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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