IDX375

IDX375 is a novel non-nucleoside inhibitor with selective inhibitory activity against HCV NS5B. IDX375 has good selectivity for genotypes 1a and 1b. The structure and binding site of IDX375 were confirmed by X-ray cocrystal studies[1].

Product Specifications

CAS Number

[1162665-52-2]

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/idx375.html

Smiles

CS(=O)(NC1=CC=C(C2=C1)NC(C3=C(O)[C@H](C(C)(C)C)N(CCC(C)(C)C)C3=O)=N[P@]2(OCC)=O)=O

Molecular Formula

C24H37N4O6PS

Molecular Weight

540.61

References & Citations

[1]Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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