RAX Antibody
Rax (Retinal and anterior neural fold homeobox), a paired-type homeobox protein, is a human homolog of Drosophila Rx protein. It is a marker of developing eye and forebrain in vertebrates, initially expressed in the region of the forebrain where optic vesicles are formed, and is involved in promoting the division of retinal progenitor cells early in development. As development progresses, expression is seen in the retina and hypothalamus. RAX is essential for eye development. Knockout of RAX in mice eliminated eye development, and RAX mutation in humans result in Anophthalmia, where one or both eyes fail to develop.
Product Specifications
Reactivity
Human
Immunogen
A recombinant protein fragment from the C-terminus of human RAX was used as the immunogen for this antibody.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Protein A affinity chromatography
Dilution
Western blot: 1-3ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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