EA-89-Succinic acid
EA-89-Succinic acid (Compound 26) is the active control of the target protein ligand EA-89 (HY-170314), which can be used for the synthesis of PROTAC [1].
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ea-89-succinic-acid.html
Smiles
O=C(O)CCC(N1CCC(CN2C=C(C)C3=C2C=CC(C4=CN(CCC)C(C5=C4SC(C(NC(CC6)CCS6(=O)=O)=O)=C5)=O)=C3)CC1)=O
Molecular Formula
C35H42N4O7S2
Molecular Weight
694.86
References & Citations
[1]Weisberg E, et al. BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma. Blood Cancer J. 2022 Jul 19;12 (7) :110.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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