EA-89-Succinic acid
Product Specifications
UNSPSC Description
EA-89-Succinic acid (Compound 26) is the active control of the target protein ligand EA-89 (HY-170314), which can be used for the synthesis of PROTAC [1].
Target Antigen
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ea-89-succinic-acid.html
Smiles
O=C(O)CCC(N1CCC(CN2C=C(C)C3=C2C=CC(C4=CN(CCC)C(C5=C4SC(C(NC(CC6)CCS6(=O)=O)=O)=C5)=O)=C3)CC1)=O
Molecular Weight
694.86
References & Citations
[1]Weisberg E, et al. BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma. Blood Cancer J. 2022 Jul 19;12(7):110.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-170317/EA-89-Succinic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-170317/
Clinical Information
No Development Reported
Curated Selection
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