Human Nr4a1 Protein, His Tag (MALS verified)
Orphan nuclear receptor 4A1 (NR4A1) belongs to the NR4A superfamily and plays an important role in inflammation, cell metabolism, proliferation and differentiation. NR4A1 expression can be induced by various stimuli in macrophages. NR4A1 has a bidirectional effect of inhibiting or promoting the inflammatory response of atherosclerosis (AS), which may be related to the different microenvironment, cell phenotype and transfection vector. NR4A1 can promote pathological angiogenesis, which is an important factor affecting plaque instability. The role of NR4A1 in inflammation and pathological angiogenesis of AS was reviewed, in order to provide a target for the treatment of stable plaque and provide a reference for the prevention and treatment of AS.
Product Specifications
Background
Specifications
Accession Number
P22736-1
Expression Region
Ser 351 - Phe 598
Host
E. coli
Target
Nr4a1
Conjugation
Unconjugated
Tag
N-10xHis
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, 0.2 M Arginine, pH7.4
Additives
Trehalose
Molecular Weight
29.5 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
1mg*1
Host or Source
E. coli
Species
Human
Protein ID
P22736-1
Preservative
Trehalose
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