Niddamycin

Niddamycin, a macrolide antibiotic, binds 50S ribosomal subunits to inhibit protein synthesis[1].

Product Specifications

CAS Number

20283-69-6

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/niddamycin.html

Smiles

O[C@]1([C@H]([C@@H](O[C@H](C1)O[C@H]2[C@@H]([C@H]([C@@H](O[C@@H]2C)O[C@@H]3[C@@H](OC)[C@@H](CC(O[C@H](C)C/C=C\C=C\C([C@@H](C[C@@H]3CC=O)C)=O)=O)O)O)N(C)C)C)OC(CC(C)C)=O)C

Molecular Formula

C40H65NO14

Molecular Weight

783.94

References & Citations

[1]S J Kakavas, et al. Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis. J Bacteriol. 1997 Dec;179 (23) :7515-22.