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Luciferase-IN-3

Luciferase-IN-3 (compound 5h) is an inhibitor of ATP-dependent luciferase (Firefly luciferase), the major light-emitting enzyme in fireflies and kowtow bugs. Firefly luciferase-IN-2 inhibits P. pyralis luciferase with an IC50 of 3.2 μM, while the inhibitory potency against R. reniformis is not significant[1].

Product Specifications

CAS Number

[690987-97-4]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/luciferase-in-3.html

Purity

90.0

Smiles

BrC1=CC=C(C2=NC(C3=CC=CC=N3)=NO2)O1

Molecular Formula

C11H6BrN3O2

Molecular Weight

292.09

References & Citations

[1]Auld DS, et al. Characterization of chemical libraries for luciferase inhibitory activity. J Med Chem. 2008 Apr 24;51 (8) :2372-86.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Curated Selection

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