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(-) -Maackiain (Standard)

(-​) ​-Maackiain (Standard) is the analytical standard of (-​) ​-Maackiain. This product is intended for research and analytical applications. (-) -Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-) -Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-) -Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-κB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-) -Maackiain is orally active[1][2].

Product Specifications

CAS Number

2035-15-6

UNSPSC

12352005

Target

Fungal; NF-κB; NOD-like Receptor (NLR) ; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Immunology/Inflammation; NF-κB; Others

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/maackiain-standard.html

Smiles

OC1=CC=C([C@@]2([H])[C@@](C3=C(C=C4C(OCO4)=C3)O2)([H])CO5)C5=C1

Molecular Formula

C16H12O5

Molecular Weight

284.26

References & Citations

[1]ScottSoby, et al. Detoxification of the phytoalexins maackiain and medicarpin by fungal pathogens of alfalfa. Phytochemistry. 1996 Feb;14 (3) :759-765.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Clinical Information

No Development Reported

Frequently Asked Questions

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