Octacosane

Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l[1][2][3].

Product Specifications

CAS Number

[630-02-4]

Product Name Alternative

N-Octacosane; NSC 5549

UNSPSC

12352211

Hazard Statement

H304, H411

Target

Bacterial; Endogenous Metabolite

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/octacosane.html

Purity

98.0

Solubility

Ethanol : < 1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCCCCCCCCCCCCCCCCCCCCCCCCCCC

Molecular Formula

C28H58

Molecular Weight

394.76

Precautions

H304, H411

References & Citations

[1]Carlos R Figueiredo, et al. Pyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo. Pharmacogn Mag. 2014 Apr;10 (Suppl 2) :S363-76. |[2]S Rajkumar, et al. Mosquitocidal activities of octacosane from Moschosma polystachyum Linn (lamiaceae) . J Ethnopharmacol. 2004 Jan;90 (1) :87-9.|[3]Sameh S M Soliman, et al. Effective targeting of breast cancer cells (MCF7) via novel biogenic synthesis of gold nanoparticles using cancer-derived metabolites. PLoS One. 2020 Oct 6;15 (10) :e0240156.