TT3
TT3 is an ionizable lipid-like material and a lipid nanoparticle (LLNs) -based mRNA delivery vector. TT3 exhibits liver and spleen specificity and excellent delivery efficiency[1][2].
Product Specifications
CAS Number
[1821214-50-9]
UNSPSC
12352005
Hazard Statement
H225, H319
Target
Liposome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tt3.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : ≥ 25 mg/mL
Smiles
O=C(C1=CC(C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)=CC(C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)=C1)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC
Molecular Formula
C90H174N6O3
Molecular Weight
1388.38
Precautions
H225, H319
References & Citations
[1]Li B, Luo X, Deng B, et al. An Orthogonal Array Optimization of Lipid-like Nanoparticles for mRNA Delivery in Vivo. Nano Lett. 2015;15 (12) :8099-8107.|[2]Jiang C, Mei M, Li B, et al. A non-viral CRISPR/Cas9 delivery system for therapeutically targeting HBV DNA and pcsk9 in vivo. Cell Res. 2017;27 (3) :440-443.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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