SYCM rabbit pAb
This gene encodes a putative member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of cysteine to tRNA molecules. A splice-site mutation in this gene has been associated with a novel progressive myoclonic epilepsy disease with similar symptoms to MERRF syndrome. [provided by RefSeq, Mar 2015],
Product Specifications
Background
Synonyms
Probable cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)
Gene ID
79587
UniProt
Q9HA77
Cellular Locus
Mitochondrion matrix.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human SYCM AA range: 95-145
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000
Molecular Weight
60kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES12869-1.pdf
Observed Molecular Weight
60 kD
Subcellular Location
Mitochondrion matrix .
Other Product Names
Probable cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)
Gene ID (Human)
79587
SwissProt (Human)
Q9HA77
Available Sizes
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