Vesencumab
Vesencumab (MNRP-1685A) is IG1 antibody against neuropilin-1 (NRP-1) . Vesencumab binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab has anti-angiogenic and anti-neoplastic activities. Vesencumab can be used in the research of metastatic solid tumors, including ovarian cancer[1][2].
Product Specifications
CAS Number
[1205533-60-3]
Product Name Alternative
MNRP-1685A
UNSPSC
12352203
Target
Complement System; EGFR; p38 MAPK; PDGFR
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation; JAK/STAT Signaling; MAPK/ERK Pathway; Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vesencumab.html
Purity
99.89
Solubility
10 mM in DMSO
Smiles
[Vesencumab]
Molecular Weight
(145.262 kDa)
References & Citations
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P99386/Vesencumab-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P99386/Vesencumab-SDS-MedChemExpress.pdf
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1
Available Sizes
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