MEISi-2
MEISi-2 is a selective inhibitor of MEIS, a key regulator of hematopoietic stem cell (HSC) self-renewal. MEISi-2 is developed for the research of cardiac injuries, hematopoiesis issues, bone marrow transplantations, and cancer[1].
Product Specifications
CAS Number
[2250156-71-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HOXA
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/meisi-2.html
Purity
98.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NN/C=C1C(C=CC2=C\1C=CC=C2)=O)C3=CC=C(O)C=C3
Molecular Formula
C18H14N2O3
Molecular Weight
306.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Raife Dilek Turan, et al. Development of Small Molecule MEIS Inhibitors that modulate HSC activity. Sci Rep. 2020; 10: 7994.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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