Α-Defensin-1 (Human)

<strong>Œ±-Defensin-1 (Human)</strong>_x000D_ <strong>Catalog number:</strong> MDP0645_x000D_ <strong>CAS Number: </strong>N/A_x000D_ <strong>Sequence: </strong>Ala-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys (Disulfide bonds between Cys2-Cys30, Cys4-Cys19, and Cys9-Cys29)_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight:</strong> 3442 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20¬∞C_x000D_ <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals._x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kling C, Pulliainen AT, Barth H, Ernst K. Human Peptides Œ±-Defensin-1 and -5 Inhibit Pertussis Toxin Toxins (Basel). 2021 Jul 11;13(7):480._x000D_ 2: Fischer S, Popoff MR, Barth H. Human alpha-defensin-1 protects cells from intoxication with Clostridium perfringens iota toxin Pathog Dis. 2018 Mar 1;76(2)._x000D_ 3: Valle-Jim√©nez X, Ram√≠rez-Cosmes A, Aquino-Dom√≠nguez AS, S√°nchez-Pe√±a F, Bustos-Arriaga J, Romero-Tlalolini ML√Å, Torres-Aguilar H, Seraf√≠n-L√≥pez J, Aguilar Ru√≠z SR. Human platelets and megakaryocytes express defensin alpha 1 Platelets. 2020;31(3):344-354._x000D_ 4: Moazzezy N, Rismani E, Rezaei M, Karam MRA, Rafati S, Bouzari S, Oloomi M. Computational evaluation of modified peptides from human neutrophil peptide 1 (HNP-1) J Biomol Struct Dyn. 2022 Feb;40(3):1163-1171._x000D_ 5: K√º√ß√ºkkolba≈üi H, K√º√ß√ºkkolba≈üi S, Dursun R, Ayyildiz F, Kara H. Determination of defensin HNP-1 in human saliva of patients with oral mucosal diseases J Immunoassay Immunochem. 2011;32(4):284-95._x000D_ 6: Owusu DO, Owusu M, Owusu BA. Human defensins and Th-1 cytokines in hepatitis C viral infection Pan Afr Med J. 2020 Sep 29;37:103._x000D_ 7: Demirkhanyan LH, Marin M, Padilla-Parra S, Zhan C, Miyauchi K, Jean-Baptiste M, Novitskiy G, Lu W, Melikyan GB. Multifaceted mechanisms of HIV-1 entry inhibition by human Œ±-defensin J Biol Chem. 2012 Aug 17;287(34):28821-38._x000D_ 8: G√∂k√߃±nar NB, Karabulut AA, Onaran Z, Yumu≈üak E, Budak Yƒ±ldƒ±ran FA. Elevated Tear Human Neutrophil Peptides 1-3, Human Beta Defensin-2 Levels and Conjunctival Cathelicidin LL-37 Gene Expression in Ocular Rosacea Ocul Immunol Inflamm. 2019;27(7):1174-1183._x000D_ 9: G√ºrsoy M, K√∂n√∂nen E, He Q, Liukkonen A, Huumonen S, G√ºrsoy UK. Toll-like receptor-1, -2, and -6 genotypes in relation to salivary human beta-defensin-1, -2, -3 and human neutrophilic peptide-1 J Clin Periodontol. 2022 Nov;49(11):1185-1191._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/30718392">10: Chen Q, Yang Y, Hou J, Shu Q, Yin Y, Fu W, Han F, Hou T, Zeng C, Nemeth E, Linzmeier R, Ganz T, Fang X. Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3161-3170. </a>_x000D_ _x000D_ <strong>Products Related to Œ±-Defensin-1 (Human) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>