E3 Ligase Ligand-linker Conjugate 115
Product Specifications
UNSPSC Description
E3 Ligase Ligand-linker Conjugate 115 is an E3 ubiquitinase ligand + linker conjugate (E3 Ligase Ligand-Linker Conjugates). E3 Ligase Ligand-linker Conjugate 115 can be used to synthesize PROTAC SMARCA2/4-degrader-27 (HY-162834)[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugate-115.html
Smiles
O=C(N[C@H](C(N1[C@H](C(NCC2=C(OCCC3=CC=C(C=C3)C4OCCO4)C=C(C=C2)C5=C(N=CS5)C)=O)C[C@@H](O)C1)=O)C(C)(C)C)C6(F)CC6
Molecular Weight
708.84
References & Citations
[1]Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159677/E3-Ligase-Ligand-linker-Conjugate-115-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159677/
Clinical Information
No Development Reported
CAS Number
2375564-59-1
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