E3 Ligase Ligand-linker Conjugate 115
E3 Ligase Ligand-linker Conjugate 115 is an E3 ubiquitinase ligand + linker conjugate (E3 Ligase Ligand-Linker Conjugates). E3 Ligase Ligand-linker Conjugate 115 can be used to synthesize PROTAC SMARCA2/4-degrader-27.
Product Specifications
CAS Number
2375564-59-1
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugate-115.html
Smiles
O=C(N[C@H](C(N1[C@H](C(NCC2=C(OCCC3=CC=C(C=C3)C4OCCO4)C=C(C=C2)C5=C(N=CS5)C)=O)C[C@@H](O)C1)=O)C(C)(C)C)C6(F)CC6
Molecular Formula
C37H45FN4O7S
Molecular Weight
708.84
References & Citations
[1]Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15 (7) :672-680.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Cytokeratin 17 (E3), CF647 conjugate, 0.1mg/mL
Cytokeratin 8 (H1), CF405S conjugate, 0.1mg/mL
CD11c (Dendritic Cell Marker) (ITGAX/1284), CF594 conjugate, 0.1mg/mL
Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker) (KRT13/2213), CF640R conjugate, 0.1mg/mL
