U-48520
U-48520 is an agonist for μ-opioid receptor with EC50 of 1561 nM[1].
Product Specifications
CAS Number
67579-11-7
UNSPSC
12352005
Hazard Statement
H302+H312+H332
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/u-48520.html
Smiles
O=C(N([C@H]1[C@H](N(C)C)CCCC1)C)C2=CC=C(Cl)C=C2
Molecular Formula
C16H23ClN2O
Molecular Weight
294.82
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
References & Citations
[1]Otte L, et al., Investigation of the μ- and κ-opioid receptor activation by eight new synthetic opioids using the [35 S]-GTPγS assay: U-47700, isopropyl U-47700, U-49900, U-47931E, N-methyl U-47931E, U-51754, U-48520, and U-48800. Drug Test Anal. 2022 Jul;14 (7) :1187-1199.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
μ Opioid Receptor/MOR
Available Sizes
Frequently Asked Questions
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