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U-48520

U-48520 is an agonist for μ-opioid receptor with EC50 of 1561 nM[1].

Product Specifications

CAS Number

67579-11-7

UNSPSC

12352005

Hazard Statement

H302+H312+H332

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/u-48520.html

Smiles

O=C(N([C@H]1[C@H](N(C)C)CCCC1)C)C2=CC=C(Cl)C=C2

Molecular Formula

C16H23ClN2O

Molecular Weight

294.82

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

References & Citations

[1]Otte L, et al., Investigation of the μ- and κ-opioid receptor activation by eight new synthetic opioids using the [35 S]-GTPγS assay: U-47700, isopropyl U-47700, U-49900, U-47931E, N-methyl U-47931E, U-51754, U-48520, and U-48800. Drug Test Anal. 2022 Jul;14 (7) :1187-1199.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

μ Opioid Receptor/MOR

Available Sizes

Frequently Asked Questions

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