Talviraline
Talviraline is a non-nucleoside reverse transcriptase (NNRT) inhibitor that is primarily used to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) . Talviraline inhibits the viral replication process by binding to a specific site of HIV-1 reverse transcriptase (RT) . Talviraline can be used to study the potential countermeasures and safety of HIV-1 infection[1].
Product Specifications
CAS Number
163451-80-7
Product Name Alternative
HBY 097
UNSPSC
12352005
Target
HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/talviraline.html
Purity
99.43
Solubility
10 mM in DMSO
Smiles
CC(C)OC(N1C2=CC(OC)=CC=C2NC([C@@H]1CSC)=S)=O
Molecular Formula
C15H20N2O3S2
Molecular Weight
340.46
References & Citations
[1]Kleim J P, et al. Preclinical evaluation of HBY 097, a new nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 replication[J]. Antimicrobial agents and chemotherapy, 1995, 39 (10) : 2253-2257.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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