Talviraline

Talviraline is a non-nucleoside reverse transcriptase (NNRT) inhibitor that is primarily used to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) . Talviraline inhibits the viral replication process by binding to a specific site of HIV-1 reverse transcriptase (RT) . Talviraline can be used to study the potential countermeasures and safety of HIV-1 infection[1].

Product Specifications

CAS Number

[163451-80-7]

Product Name Alternative

HBY 097

UNSPSC

12352005

Target

HIV; Reverse Transcriptase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/talviraline.html

Purity

99.43

Solubility

10 mM in DMSO

Smiles

CC(C)OC(N1C2=CC(OC)=CC=C2NC([C@@H]1CSC)=S)=O

Molecular Formula

C15H20N2O3S2

Molecular Weight

340.46

References & Citations

[1]Kleim J P, et al. Preclinical evaluation of HBY 097, a new nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 replication[J]. Antimicrobial agents and chemotherapy, 1995, 39 (10) : 2253-2257.