2'-O-Methylcytidine-d3
2'-O-Methylcytidine-d3 is deuterium labeled 2'-O-Methylcytidine. 2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B) -catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.
Product Specifications
CAS Number
2653209-08-4
UNSPSC
12352005
Target
HCV; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-anti-virus
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](O)[C@@H](OC([2H])([2H])[2H])[C@H](N2C(N=C(N)C=C2)=O)O1
Molecular Formula
C10H12D3N3O5
Molecular Weight
260.26
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Steven S Carroll, et al. Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs. J Biol Chem. 2003 Apr 4;278 (14) :11979-84
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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