3', 4', 5', 5, 7-Pentamethoxyflavone
3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic agents by inhibition of Nrf2 pathway[1].
Product Specifications
CAS Number
[53350-26-8]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-4-5-5-7-pentamethoxyflavone.html
Purity
99.84
Solubility
DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=C(C2=CC(OC)=C(OC)C(OC)=C2)OC3=CC(OC)=CC(OC)=C13
Molecular Formula
C20H20O7
Molecular Weight
372.37
Precautions
H315, H319, H335
References & Citations
[1]Hou X, et al. 3',4',5',5,7-pentamethoxyflavone sensitizes Cisplatin-resistant A549 cells to Cisplatin by inhibition of Nrf2 pathway. Mol Cells. 2015 May;38 (5) :396-401.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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