Acetylleucine

Acetylleucine (N-Acetyl-DL-leucine), orally active compound, can be used for the research of acute vestibular vertigo, cerebellar ataxia and nystagmus[1][2].

Product Specifications

CAS Number

[99-15-0]

Product Name Alternative

N-Acetyl-DL-leucine

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Acetylleucine.html

Purity

99.38

Solubility

DMSO : 120 mg/mL (ultrasonic) |H2O : 6.67 mg/mL (ultrasonic)

Smiles

CC(C)CC(C(O)=O)NC(C)=O

Molecular Formula

C8H15NO3

Molecular Weight

173.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Feil K, et, al. Update on the Pharmacotherapy of Cerebellar Ataxia and Nystagmus. Cerebellum. 2016 Feb;15 (1) :38-42.|[2]Clément G, et, al. Effects of vestibular training on motion sickness, nystagmus, and subjective vertical. J Vestib Res. 2007;17 (5-6) :227-37.|[3]Günther L, et al. N-acetyl-L-leucine accelerates vestibular compensation after unilateral labyrinthectomy by action in the cerebellum and thalamus. PLoS One. 2015 Mar 24;10 (3) :e0120891.