NNC 63-0532
Product Specifications
UNSPSC Description
NNC63-0532 is a novel non-peptide nociceptin receptor (ORL1) agonist, with EC50s of 305 nM. NNC63-0532 plays important roles in many disorders such as pain, drug addiction[1].
Target Antigen
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nnc-63-0532.html
Purity
99.81
Solubility
DMSO : 200 mg/mL (ultrasonic;warming;heat to 80°C)
Smiles
O=C(OC)CN1CN(C2=CC=CC=C2)C3(CCN(CC4=C5C=CC=CC5=CC=C4)CC3)C1=O
Molecular Weight
443.54
References & Citations
[1]C Thomsen, et al. (8-Naphthalen-1-ylmethyl-4-oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-3-yl)-acetic acid methyl ester (NNC 63-0532) is a novel potent nociceptin receptor agonist. Br J Pharmacol. 2000 Nov;131(5):903-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12698/NNC-63-0532-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12698/NNC-63-0532-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
250685-44-0
Available Sizes
Curated Selection
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