Substance P (4-11)
Substance P (4-11), the C-terminus fragment of Substance P , is a Substance P agonist that shows highly selective for NK1 receptors[1][2].
Product Specifications
CAS Number
53749-60-3
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/substance-p-4-11.html
Solubility
10 mM in DMSO
Smiles
CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@@H]2CCCN2)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O
Molecular Formula
C46H67N11O10S
Molecular Weight
966.16
References & Citations
[1]D G Payan, et al. Specific stimulation of human T lymphocytes by substance P. J Immunol. 1983 Oct;131 (4) :1613-5.|[2]L Wang, et al. Substance P induces ion secretion in mouse small intestine through effects on enteric nerves and mast cells. Am J Physiol. 1995 Jul;269 (1 Pt 1) :G85-92. |[3]P Cornaglia-Ferraris, et al. Sensory neuropeptides (substance P) and 4-11 SP enhance human neutrophils chemiluminescence; the role of L-arginine. Int J Immunopharmacol. 1986;8 (4) :463-8.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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