JIP-1 (153-163)

JIP-1 (153-163) (TI-JIP) is a peptide inhibitor of c-JNK, based on residues 153-163 of JNK-interacting protein-1 (JIP-1) (Modifications: Phe-11 = C-terminal amide) [1].

Product Specifications

CAS Number

[438567-88-5]

Product Name Alternative

TI-JIP; JIP-1 peptide; JIPtide

UNSPSC

12352209

Target

JNK

Type

Peptides

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/jip-1-153-163.html

Purity

99.42

Solubility

H2O

Smiles

C([C@@H](NC([C@@H](NC(=O)[C@H]1N(C([C@H](CCCNC(=N)N)N)=O)CCC1)CCCCN)=O)CCCNC(=N)N)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N)=O)=O)CC(C)C)=O)CC(N)=O)=O)CC(C)C)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CCC2

Molecular Formula

C61H104N20O14

Molecular Weight

1341.60

References & Citations

[1]Renae K Barr, et al. Identification of the critical features of a small peptide inhibitor of JNK activity. J Biol Chem. 2002 Mar 29;277 (13) :10987-97.