Diminutol
Diminutol is an inhibitor for NADP-dependent quinone oxidoreductase (NQO1), that is involved in microtubule morphogenesis and cell devision[1].
Product Specifications
CAS Number
[361431-33-6]
UNSPSC
12352005
Target
Microtubule/Tubulin; Quinone Reductase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/diminutol.html
Purity
98.1
Solubility
10 mM in DMSO
Smiles
CC(C)N1C2=NC(N[C@@H](CO)C(C)C)=NC(SC3=CC(N)=CC=C3)=C2N=C1
Molecular Formula
C19H26N6OS
Molecular Weight
386.51
References & Citations
[1]Wignall SM, et al., Identification of a novel protein regulating microtubule stability through a chemical approach. Chem Biol. 2004 Jan;11 (1) :135-46.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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