ML089
ML089 is a potent, selective, and orally available phosphomannose isomerase (PMI) inhibitor with an IC50 of 1.3 µM. ML089 can be used for the research of congenital disorder of glycosylation Ia[1][2].
Product Specifications
CAS Number
[1306638-12-9]
UNSPSC
12352005
Target
Phosphomannose Isomerase (PMI)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ml089.html
Purity
99.86
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1N(C2=CC=CC=C2)SC3=C1C=C(F)C=C3
Molecular Formula
C13H8FNOS
Molecular Weight
245.27
References & Citations
[1]Russell Dahl, et al. Potent, selective, and orally available benzoisothiazolone phosphomannose isomerase inhibitors as probes for congenital disorder of glycosylation Ia. J Med Chem. 2011 May 26;54 (10) :3661-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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