ML089

ML089 is a potent, selective, and orally available phosphomannose isomerase (PMI) inhibitor with an IC50 of 1.3 µM. ML089 can be used for the research of congenital disorder of glycosylation Ia[1][2].

Product Specifications

CAS Number

[1306638-12-9]

UNSPSC

12352005

Target

Phosphomannose Isomerase (PMI)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ml089.html

Purity

99.86

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1N(C2=CC=CC=C2)SC3=C1C=C(F)C=C3

Molecular Formula

C13H8FNOS

Molecular Weight

245.27

References & Citations

[1]Russell Dahl, et al. Potent, selective, and orally available benzoisothiazolone phosphomannose isomerase inhibitors as probes for congenital disorder of glycosylation Ia. J Med Chem. 2011 May 26;54 (10) :3661-8.