ZM600

ZM600 is a potent and orally active antihepatic fibrosis agent. ZM600 decreases the LPS (HY-D1056) induced protein expression of collagen I, α-SM, p-p65. ZM600 has the potential for the research of liver fibrosis[1].

Product Specifications

UNSPSC

12352005

Target

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/zm600.html

Smiles

[H][C@@]12[C@]([H])([C@@]([H])(CC([C@@]2(CCCC(OC)=O)[H])C(C(C3=CC=C(C(F)=C3)C4=CC=CC=C4)C)=O)CCC5)C5CCC1

Molecular Formula

C33H41FO3

Molecular Weight

504.68

References & Citations

[1]Li G, et al. Discovery of Sophoridine α-Aryl Propionamide Derivative ZM600 as a Novel Antihepatic Fibrosis Agent. J Med Chem. 2024 Jul 11;67 (13) :11389-11400.