ZM600
ZM600 is a potent and orally active antihepatic fibrosis agent. ZM600 decreases the LPS induced protein expression of collagen I, α-SM, p-p65. ZM600 has the potential for the research of liver fibrosis[1].
Product Specifications
UNSPSC
12352005
Target
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/zm600.html
Smiles
[H][C@@]12[C@]([H])([C@@]([H])(CC([C@@]2(CCCC(OC)=O)[H])C(C(C3=CC=C(C(F)=C3)C4=CC=CC=C4)C)=O)CCC5)C5CCC1
Molecular Formula
C33H41FO3
Molecular Weight
504.68
References & Citations
[1]Li G, et al. Discovery of Sophoridine α-Aryl Propionamide Derivative ZM600 as a Novel Antihepatic Fibrosis Agent. J Med Chem. 2024 Jul 11;67 (13) :11389-11400.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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