Artanin

Artanin is a coumarin, has biological activities related to Alzheimer’s disease. Artanin exerts function including AChE inhibitory and AChE- and self-induced amyloid beta (Aβ) aggregation inhibitory activities, with IC50s of 51 μM, 98 μM, and 124 μM, respectively[1].

Product Specifications

CAS Number

[96917-26-9]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Natural Products

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/artanin.html

Purity

90.0

Solubility

10 mM in DMSO

Smiles

C/C(C)=C/COC1=C(O2)C(C=CC2=O)=C(OC)C=C1OC

Molecular Formula

C16H18O5

Molecular Weight

290.31

References & Citations

[1]Takomthong P, et al. Structure-Activity Analysis and Molecular Docking Studies of Coumarins from Toddalia asiatica as Multifunctional Agents for Alzheimer's Disease. Biomedicines. 2020 May 2;8 (5) :107.