Antibacterial agent 255
Antibacterial agent 255 (compound (±) -1) is a potent antibacterial agent. Antibacterial agent 255 is a potent and selective 4-diphosphocytidyl-2-C-methyl-D-erythritol (IspE) inhibitor with IC50 values of 13.0, 8.0, 20 µM for EclspE, KplspE, AblspE, respectively[1].
Product Specifications
CAS Number
945980-50-7
UNSPSC
12352211
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-255.html
Smiles
NC1=NC(N(C2CCCS2)C=C1C#CCNS(=O)(C3CC3)=O)=O
Molecular Formula
C14H18N4O3S2
Molecular Weight
354.45
References & Citations
[1]Hamid R, et al. IspE kinase as an anti-infective target: Role of a hydrophobic pocket in inhibitor binding. Structure. 2024 Nov 1:S0969-2126 (24) 00444-1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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