Propargyl-PEG5-NHS ester
Product Specifications
UNSPSC Description
Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG5-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/propargyl-peg4-c2-nhs-ester.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C#CCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
Molecular Weight
401.41
References & Citations
[1]Zhenjun Diwu, et al. Polyfluoreno[4,5-cde]oxepine Conjugates and Their Use in Methods of Analyte Detection. US20170275418A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130388/Propargyl-PEG5-NHS-ester-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130388/Propargyl-PEG5-NHS-ester-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1393330-40-9
Available Sizes
Curated Selection
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