N- (Amino-PEG5) -N-bis (PEG4-acid)
N- (Amino-PEG5) -N-bis (PEG4-acid) is a PEG derivative containing an amino group with two terminal carboxylic acids. The amino group is reactive with carboxylic acids, activated NHS esters. The terminal carboxylic acids can react with primary amine groups in the presence of activators to form a stable amide bond. N- (Amino-PEG5) -N-bis (PEG4-acid) can be useful in the development of antibody drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[2093152-86-2]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-amino-peg5-n-bis-peg4-acid.html
Purity
99.52
Solubility
DMSO : 175 mg/mL (ultrasonic)
Smiles
O=C(O)CCOCCOCCOCCOCCN(CCOCCOCCOCCOCCOCCN)CCOCCOCCOCCOCCC(O)=O
Molecular Formula
C34H68N2O17
Molecular Weight
776.91
Precautions
H302, H315, H319, H335
References & Citations
[1]SUZAKI Yasunori, et al. Antibody-multidrug conjugate. WO2023234426A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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