Ac-LETD-CHO
Ac-LETD-CHO is a caspases 8 inhibitor. Ac-LETD-CHO has specific inhibition to casp-8 with an IC50 value of 6.71 nM. Ac-LETD-CHO can be used for the research of anticancer[1].
Product Specifications
UNSPSC
12352209
Target
Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ac-letd-cho.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C=O)=O)=O)=O)C
Molecular Formula
C21H34N4O10
Molecular Weight
502.52
References & Citations
[1]Hu J, et al. MALDI-MS Patterning of Caspase Activities and Its Application in the Assessment of Drug Resistance. Angew Chem Int Ed Engl. 2016 Jun 1;55 (23) :6667-70.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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