1,3-Diphenylisobenzofuran

1,3-Diphenylisobenzofuran (DPBF) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS) . DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals[1].

Product Specifications

CAS Number

[5471-63-6]

Product Name Alternative

DPBF

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye; Reactive Oxygen Species (ROS)

Type

Dye Reagents

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/1-3-diphenylisobenzofuran.html

Purity

98.90

Solubility

DMSO : 5.56 mg/mL (ultrasonic)

Smiles

C1(C2=CC=CC=C2)=C3C=CC=CC3=C(C4=CC=CC=C4)O1

Molecular Formula

C20H14O

Molecular Weight

270.33

Precautions

H302, H315, H319, H335

References & Citations

[1]Weili Fan, et al. Calcium carbonate-methylene blue nanohybrids for photodynamic therapy and ultrasound imaging. Sci China Life Sci. 2018 Apr;61 (4) :483-491.|[2]P. Carloni, et al. On the use of 1,3-diphenylisobenzofuran (DPBF) . Reactions with carbon and oxygen centered radicals in model and natural systems. Research on Chemical Intermediates volume 19, pages395-405 (1993) .|[3]Bai X, et al. HKOH-1: A Highly Sensitive and Selective Fluorescent Probe for Detecting Endogenous Hydroxyl Radicals in Living Cells. Angew Chem Int Ed Engl. 2017 Oct 9;56 (42) :12873-12877.