KBTBD6, Human (sf9)

KBTBD6 is a key member of the CUL3 (KBTBD6/7) E3 ubiquitin ligase complex, acting as a substrate adapter to coordinate the “Lys-48” ubiquitination and subsequent proteasomal degradation of the RAC1 guanine exchange factor TIAM1. This regulatory role enables KBTBD6 to control RAC1 signaling, affecting important processes such as cytoskeletal organization, cell migration, and cell proliferation. KBTBD6 Protein, Human (sf9) is the recombinant human-derived KBTBD6 protein, expressed by sf9 insect cells , with tag free.